UW Genome Sciences
Faculty Search
Open Rank and Assistant Professor positions. Application deadline is December 4.
Graduate Program
Our application deadline is December 1. Information sessions will be held via Zoom on October 6 & 22.
DeWitt Lab
Replaying germinal center evolution on a quantified affinity landscape
Fowler Lab
Image-based, pooled phenotyping reveals multidimensional, disease-specific variant effects
Distinguished Teaching Award
Hannah Jordt receives UW Distinguished Teaching Award
National Academy of Sciences
Jesse Bloom elected to the National Academy of Sciences
National Academy of Medicine
Jay Shendure elected to National Academy of Medicine
Eichler Lab
Complete sequencing of ape genomes.
Welcome to the Department of Genome Sciences
Our goal is to address leading edge questions in biology and medicine by developing and applying genetic, genomic and computational approaches that take advantage of genomic information now available for humans, model organisms and a host of other species. Our faculty study a broad range of topics, including the genetics of E. coli , yeast, C. elegans , Drosophila , and mouse; human and medical genetics; mathematical, statistical and computer methods for analyzing genomes, and theoretical and evolutionary genetics; and genome-wide studies by such approaches as sequencing, transcriptional and translational analysis, polymorphism detection and identification of protein interactions.
Upcoming Events
October 16, 2026 3:00 pm – 4:00 pm
Foege Auditorium
Research Reports:
Carissa Lee, Shawn Mohammed
Carissa Lee | Stergachis Lab, Chamberlain Lab
“AAV chromatinization in Duchenne muscular dystrophy gene therapy”
Shawn Mohammed | Shendure Lab
“Time Stamping Biology through Inducible Molecular Recording”
October 21, 2026 3:30 pm – 4:30 pm
Foege Auditorium
GS Seminar:
Dr. Elizabeth Jerison
University of Chicago
“Probing the dynamics of inflammatory response”
October 23, 2026 3:00 pm – 4:00 pm
Foege Auditorium
Research Reports:
Max Dippel, Ben Shapiro
Recent News
October 15, 2026 | News
Journal of Proteome Research
Mike MacCoss will be the next Editor-in-Chief of the Journal of Proteome Research.
October 7, 2026 | News
New Innovator Award
Saori Sakaue has received the 2026 NIH Director’s New Innovator Award.
October 5, 2026 | News
Faculty Positions in Genome Sciences (Open Rank and Assistant Professor)
Genome Sciences invites applications for two full-time faculty positions.
Research Highlights
A telomere-to-telomere map of somatic mutation burden and functional impact in a cancer
Stergachis Lab members are authors on a paper in Cell .
Somatic epimutations cap genetic determinism in the human diploid chromatin epigenome
Stergachis Lab members are authors on a paper in Cell .
A DNA Typewriter records the cell lineage history of a mouse, from zygote to late organogenesis
Shendure Lab members are authors on a paper in Science . | UW Medicine Newsroom
Telomeric amplicons of SUL1 and Y’ in yeast are generated by microhomology-mediated break induced replication occurring in cis
Brewer-Raghuraman Lab and Dunham Lab members are authors on a paper in PLOS Genetics .
Mutational bias and local genome context constrain adaptive paths in experimental evolution
Current and former Dunham Lab members are authors on a paper in Genetics .
Vibe Coding Moves Beyond the Proteomics Prototype
The MacCoss Lab is featured in an article in The Analytical Scientist .
Prioritizing Peptides for Targeted Mass Spectrometry Experiments Using Deep Learning
Yash Sonthalia and Bo Wen are lead authors on publication in Journal of Proteome Research .
3D epigenome of glial cell types in developing human cortex
Current and former Hawkins Lab members are authors on paper in Nature .
Evidence for G6PD variant classification from multiplexed functional assays
Current and former Dunham and Fowler Lab members are authors on paper in Genome Biology .
Early immune cell development precedes gastrulation in annual killifish
Syd Sattler is lead author on a publication in bioRxiv , along with other Abitua and Trapnell Lab members.