Christine Queitsch

Associate Professor of Genome Sciences

phone: (206) 685-8935 | fax: (206) 685-7301
Foege S-410, Box 355065
queitsch [ a t ] u.washington.edu
website

Research:

Dr. Christine Queitsch comes to Genome Sciences from the FAS Center of Systems Biology at Harvard University where she completed a Bauer Fellowship. Her research seeks to characterize molecular mechanisms that govern phenotypic robustness and that can rapidly generate selectable phenotypic variation in a multicellular organism.

Selected Publications:

Sangster TA, Salathia N, Undurraga S, Milo R, Schellenberg K, Lindquist S, Queitsch C. HSP90 affects the expression of genetic variation and developmental stability in quantitative traits. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2963-8. Epub 2008 Feb 19.

Sangster TA, Salathia N, Lee HN, Watanabe E, Schellenberg K, Morneau K, Wang H, Undurraga S, Queitsch C*, Lindquist S. HSP90-buffered genetic variation is common in Arabidopsis thaliana. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2969-74. Epub 2008 Feb 19. (*co-corresponding author)

McLellan C.A., Turbyville T.J., Kithsiri Wijeratne E. M., Kerschen A., Vierling E., Queitsch C., Whitesell L., Gunatilaka L. A. A. A Rhizosphere Fungus Enhances Arabidopsis Thermotolerance Through Production of an HSP90 Inhibitor.
Plant Physiol. 2007 Jul 13; [Epub ahead of print]

Sangster TA, Bahrami A, Wilczek A, Watanabe E, Schellenberg K, McLellan C, Kelley A, Kong SW, Queitsch C*, Lindquist S. Phenotypic diversity and altered environmental plasticity in Arabidopsis thaliana with reduced Hsp90 levels. PLoS ONE. 2007 Jul25;2:e648.(*corresponding author)

Salathia N., Lee H. N., Sangster T. A., Morneau K., Landry C.R., Schellenberg K., Behere A. S., Cavalieri D., Jander G., Queitsch C. Indel arrays: an affordable alternative for genotyping. Plant J. 2007 Jul 20; [Epub ahead of print]

Sangster, TA and C. Queitsch The HSP90 chaperone complex, an emerging force in plant development and phenotypic plasticity. Current Opinion in Plant Biology 2005, 8:86–92

Jackson SE, Queitsch C, Toft D. Hsp90: from structure to phenotype.
Nat Struct. Mol Biol. 2004 Dec; 11(12):1152-5.

Sangster TA, Lindquist S, Queitsch C. Under cover: causes, effects and implications of Hsp90-mediated genetic capacitance. BioEssays. 2004 Apr; 26(4):348-62.

Sangster TA, Queitsch C., Lindquist, S. Hsp90 and Chromatin: Where is the Link? Cell Cycle. 2003; 2(3):166-168

Queitsch C., Sangster TA, Lindquist S. Hsp90 as a capacitor of phenotypic variation. Nature. 2002 Jun 6; 417(6889):618-24.

Queitsch C., Hong S-W, Vierling E., Lindquist S. The heat shock protein HSP101 is crucial for thermotolerance in Arabidopsis. Plant Cell 2000 April; 12:479-492