Summer Program Past Participants
2022
PI: Evan Eichler
project: Human Structural Diversity of Complex Inverted Region at 17q21.31
PI: Doug Fowler
project: Deep mutational scanning reveals epistasis in CYP2C19
PI: Lea Starita
project: Conserved intronic region of MYBPC3 functions as a strong enhancer in iPSC cardiomyocyte reporter assay
PI: Christine Queitsch, Josh Cuperus
project:
Fort Lewis College
PI: Judit Villen
project:
PI: Stan Fields
project:
PI: Brian Beliveau
project:
PI: Christine Queitsch, Josh Cuperus
project: Investigating Genetic Insulation Mechanisms in Plants
PI: Devin Schweppe
project:
PI: David Hawkins
project:
2021
PI: Brian Beliveau
project: Visualizing Satellite DNA Repeats with Tigerfish
PI: Doug Fowler
project: Alternating Nuclear Localization Signals to Optimize Bxb1 Recombinase
PI: Mike MacCoss
project: Optimization of limited proteolysis-mass spectrometry on cerebrospinal fluid
PI: Lea Starita
project: Identification of CRISPR prime edited resistance mutations in the EGFR gene
PI: David Hawkins
project: Verifying Enhancers Interactions through Deletion of the Enhancers
PI: Cole Trapnell
project: Building an Atlas of Lung Cell Types in Hereditary Pulmonary Alveolar Proteinosis
PI: Bill Noble
project: Avocado model uses HFFc6 cell type to make predictions for missing assays
PI: Devin Schweppe
project:
PI: Christine Queitsch, Josh Cuperus
project: Identifying photoperiod sensitivity across Camelina sativa accessions
PI: Christine Queitsch, Josh Cuperus
project: Short-day conditions significantly affect growth of Camelina sativa
PI: Maitreya Dunham
project: Haplotype modifies variant function in G6PD
2019
PI: David Hawkins
project: Functional validation of Human T-cells and Macrophage specific Cis-Regulatory Elements
PI: Celeste Berg
project: Investigation of Novel Gene Interaction in D. melanogaster Tube Formation
PI: Stan Fields
project: Identifying Inhibitory Fragments of E. coli Dihydrofolate Reductase with a Sequencing-based Assay
PI: Evan Eichler
project: Characterizing the Gene HNRNPH2 in Neurodevelopmental Disorders
PI: Maitreya Dunham
project: Identification of genes that impact fitness of aneuploid S. cerevisiae strains
PI: Cole Trapnell
project: Single Cell Investigation of npas41 Zebrafish Mutants
PI: Christine Queitsch
project: Developing Methods for Characterizing Plant Enhancers
PI: Jay Shendure
project: Optimizing Conditions for Single Cell Lineage Tracing in a Mammalian Model
PI: Bonny Brewer
project: Does the mcm4 helicase mutation increase genome instability in yeast?
PI: Paul Valdmanis
project:
PI: Christine Queitsch
project: Mapping Cell Lineages with scATAC-seq
PI: Lea Starita
project:
2018
PI: Celeste Berg
project:
PI: Cole Trapnell
project: Dissecting Kinase Networks with Targeted Single-Cell Genomics and Proteomics
PI: Willie Swanson
project: Genetic Variation in Sperm Lysin in Pacific Abalone
PI: David Hawkins
project: Understanding Gene Expression via Enhancers
PI: Stan Fields
project: Mistranslation as a Method to Measure the Impact of Mutations on Protein Interactions
PI: Sam Miller
project:
PI: Doug Fowler
project: Identifying Inhibitor-Specific Resistance Mutations in Src Kinase
PI: Bill Noble
project: Generating Representative Subsets from Single Cell Hi-C Data Using Submodular Optimization
PI: Judit Villen
project: Identifying and Understanding Phosphorylation Patterns on Insulin Receptor Substrate 1 Using Targeted Mass Spectrometry
PI: Bonny Brewer
project: Sequence Specificity of Yeast Origins
2017
PI: Jay Shendure
project:
PI: Evan Eichler
project:
PI: Leo Pallanck
project:
PI: Bob Waterston
project:
PI: Jim Bruce
project:
PI: Celeste Berg
project:
PI: Doug Fowler
project:
PI: Stan Fields
project:
PI: Jim Bruce
project:
PI: Cole Trapnell
project:
PI: David Hawkins
project:
2016
PI: Evan Eichler
project: The evolutionary history and transcript diversity of a Homo sapiens specific segmental duplication
PI: Sam Miller
project: The second messenger cyclic-di-GMP regulates biofilm formation, motility, antibiotic resistance, and outer membrane permeability of multidrug-resistant Acinetobacter baumannii
PI: Bob Waterston
project: Analyzing single cell gene expression in Caenorhabditis elegans
PI: Mike MacCoss
project: Quantifying phosphorylation events in the insulin signaling pathway using MS/MS
PI: Doug Fowler
project: Validating Amyloid-Beta Deep Mutational Scan data using a yeast growth assay
PI: Cole Trapnell
project: Visualization of myoblast fusion to uncover underlying mechanisms
2015
PI: Cole Trapnell
project:
PI: Bob Waterston
project:
PI: Jim Bruce
project:
PI: Jay Shendure
project: Measuring Cellular Growth Response to 6-MP Treatment and Protein Stability in all Possible Nonsynonymous Mutations in TPMT
PI: Sam Miller
project:
PI: Doug Fowler
project:
2014
PI: Bob Waterston
project:
PI: Evan Eichler
project:
PI: Ray Monnat
project:
PI: Jim Bruce
project:
PI: Bonny Brewer
project:
PI: Celeste Berg
project:
PI: Jay Shendure
project: Saturation mutagenesis methods for evaluating the effects of all possible nonsynonymous mutations in TPMT in response to thiopurine drugs
PI: Stan Fields
project: The effect of synonymous codon pair changes on HIS3 expression in yeast
2013
PI: Mary-Claire King
project:
PI: Evan Eichler
project:
PI: Leo Pallanck
project:
PI: Maitreya Dunham
project:
PI: Bonny Brewer
project:
PI: Bill Noble
project:
PI: Doug Fowler
project:
2012
PI: Bonny Brewer
project: Amplification of SUL1 in diploid yeast cells grown in sulfate-limited conditions
PI: Josh Akey
project: Whole Genome Analysis of Siblings by comparing SNPs with Identity by Descent
PI: Evan Eichler
project: Identification of Copy Number Variants Contributing to Neurological Disorders of Human Specific Neuronal SRGAP2
PI: Sam Miller
project: Indentifying phoP mutants involved in regulating Salmonella's outermembrane permeability barrier
PI: Celeste Berg
project: Exploring the role of putative Tramtrack69 targets in Drosophila tube morphogenesis
PI: Stan Fields
project: Isolation and characterization of ethanol-tolerant yeast strains
PI: Bob Waterston
project: Can Partially Redundant Genes Compensate for the Loss of their Partner? Examination of the Roles of the Tbx8 and Tbx9 Genes in Embryonic Nematode Development
PI: Judit Villen
project: Evolutionary Protein Phosphorylation in Yeast Species
2011
PI: Judit Villen
project: Signaling Patterns in the Saccharomyces cerevisiae Proteome under Oxidative Stress
PI: Christine Queitsch
project:
PI: Evan Eichler
project: The Discovery and Validation of Copy Number Variations in Autism
PI: John Stamatoyannopoulos
project:
PI: Josh Akey
project: A High-Resolution Genome Wide Map of Structural Variation in the Modern Domesticated Dog
PI: Celeste Berg
project: On the Shark quest: Role of Shark tyrosine kinase in tube formation
PI: John Stamatoyannopoulos
project: A Novel Method for Detection and Quantification of Genome-Wide Methylation
PI: Willie Swanson
project: Population Sequencing of a Rapidly Evolving Sperm Protein, SP6
PI: Bob Waterston
project: Identification of Regulatory Relationships of hnd-1 in Muscle Differentiation and of elt-1 in Hypodermal Differentiation in the Caenorhabditis elegans Embryo
2010
PI: Elhanan Borenstein
project: "An analysis of the topological properties of the metabolic networks of gut-dwelling microbes"
PI: Mike MacCoss
project:
PI: Evan Eichler
project:
PI: Leo Pallanck
project: "Mitochondrial quality control in dopaminergic neurons"
PI: Jay Shendure
project: "Progress towards massively parallel single cell sequencing of T-cell receptors"
PI: Gail Jarvik
project: "Challenging the Powerful Gene: An Investigation of Muscle Hypertrophy"
PI: Celeste Berg
project: "Probing the Role of Stretch cells during Dorsal Appendage Tube Formation in Drosophila"
PI: Bonny Brewer
project: "Genome Mapping Identifies Genomic Inversion in Kluyveromyces walti"
2009
PI: Bob Waterston
project:
PI: Bill Noble
project:
PI: Evan Eichler
project:
PI: Maitreya Dunham
project:
PI: Debbie Nickerson
project: