For times and locations, please check the UW Time Schedule

Early Fall Start

CSI: Seattle
Instructor: Brook Nunn
TAs: Hunter Colegrove, Connor Kubo

Autumn 2024

Genome 361: Fundamentals of Genetics and Genomics
Instructor: Hannah Jordt
TAs: Stephen Gonzalez, Iris Jia, Cliff Rostomily

Course Description:
Introduces fundamentals concepts in genetics and genomics including patterns of inheritance, genetic variation, and the relationship between genotype and phenotype. Prerequisite: Biol 200; may not be taken if Genome 371 has already been taken; may not be repeated. Offered: AWSpS

Genome 371: Introductory Genetics
Instructor: M.K. Raghuraman
TAs: Sahar Attar, Caleb Carr, Conor Kelly

Course Description:
Three aspects of genetics are covered: 1) Mechanisms of gene transmission, including chromosome mapping and genetic pathways; 2) Mutational analysis of biological processes with an emphasis on mutations that affect chromosome transmission; 3) An introduction to genomics--the cloning and sequence analysis of whole genomes. The emphasis is on both formal genetic mechanisms and molecular techniques. For biological sciences majors. Prerequisite: minimum 1.7 in either BIOL 200 or BIOL 201; may not be repeated. Offered: Autumn.

Genome 372: Genomics & Proteomics
Instructors: Jim Bruce, Evan Eichler
TAs: David Lee, Syd Sattler

Course Description:
Covers emerging fields of genomics and proteomics. Discusses key technologies and their applications to the study of human and model organism genomes.

Genome 550: Methods and Logic in Genetics
Instructors: Jay Shendure, Christine Queitsch

Course Description:
Critical reading and detailed discussion of genetics-related scientific research papers. Material emphasizes methodological and logical themes of importance in modern genetics, for example: origin of mutants, genetic epistasis, pulse labelling, and in vivo gene function. Prerequisite: first year Genome Sciences graduate students only.

Genome 552: Genomics
Instructor: Lea Starita
5 week course - second half of the quarter

Course Description:
Introduces students to the nature of genomes, the structure of chromosomes, the organization of sequences, and the diversity of these features in different species. Discusses current and newly emerging technologies for mapping and sequencing genomes, determining linkage of simple and complex disorders, and identifying variations in DNA. Formerly called MBT 510.

Genome 555: Proteomics
Instructor: Judit Villen
5 week course - first half of quarter

Course Description:
The course will focus on current and emerging technologies and approaches for analyzing protein structure and function, protein:protein interactions, and whole-cell protein functions ("the proteome"). We will emphasize the application of these technologies in biology, biotechnology and medicine. Prerequisite: BIOC 440, GENOME 551 or equivalent, GENOME 553

Genome 599: Special Topics - Scientific Speaking
Instructors: Jim Bruce, Judit Villen
specific dates to be determined - late summer / early fall
Research Report preparation - for second year GS grads and first year GS / MSTP grads only

Genome 599: Special Topics - Grant Writing
Instructors: Stan Fields, Doug Fowler
specific dates to be determined - for second year GS grads only

Winter 2025

Genome 361: Fundamentals of Genetics and Genomics
Instructors: Bonny Brewer, Hannah Jordt
TAs: Erik Bergstrom, Monika Perez, Lizzie Plender

Course Description:
Introduces fundamentals concepts in genetics and genomics including patterns of inheritance, genetic variation, and the relationship between genotype and phenotype. Prerequisite: Biol 200; may not be taken if Genome 371 has already been taken; may not be repeated. Offered: AWSpS

Genome 465 / 565: Advanced Human Genetics
Instructors: Mary-Claire King, Evan Eichler
TAs: Caroline Kikawa, Jenny Nathans

Course Description:
Explores genetic analysis of naturally occurring variation in humans; origins and consequences of mutation, as mediated by selection, migration, population structure and drift; approaches to finding human disease genes and characterizing them at the molecular level; relevance of to other species to analysis of human genes. Prerequisite: either Genome 361 or Genome 371.

Genome 466: Cancer Genetics
Instructors: David Hawkins, Jim Thomas
TA: Lucas Kampman, Luana Paleologu

Course Description:
Focuses on three types of cancer-related genetics. DNA repair, mitotic recombination, chromosome loss and imbalance, and other aspects of genomic instability. Metastatic cancer as an example of natural selection and evolution. Yeast and nematodes as models for the study of cancer genetics. Prerequisite: either Genome 361 or Genome 371.

Genome 540: Intro to Computational Molecular Biology
Instructor: Phil Green
TA: Joe Min

Course Description:
Algorithmic and probabilistic methods for analysis of DNA and protein sequences. Students must be able to write computer programs for data analysis. Prior coursework in biology and probability highly desirable. Prerequisite: permission of instructor.

Genome 551: Gene Regulation
Instructor: Cole Trapnell
5 week course - second half of the quarter

Course Description:
Course covers fundamentals of gene regulation in eukaryotes including principles of cis and trans regulation of gene expression; DNA and RNA binding proteins; role of chromatin structure in gene expression; epigenetic regulatory mechanisms; RNA-based regulatory mechanisms; and post-transcriptional regulation. The course centers on reading and discussion of landmark primary literature in the aforementioned areas.

Genome 559: Introduction to Statistical and Computational Genomics
Instructors: Brian Beliveau, Bill Noble
TA: Ben Mallory
Course Description:
Rudiments of statistical and computational genomics. Emphasis on basic probability and statistics, introduction to computer programming and relevant web databases. This course is intended to introduce students with non-computer science backgrounds to the major concepts of programming and statistics. Prerequisite: substantial background in molecular and cellular biology, genetics, biochemistry, or related disciplines.

Genome 561: Molecular Population Genetics and Evolution
Instructor: Kelley Harris
5 week course - first half of the quarter

Course Description:
This course will survey recent literature in order to gain an understanding of the basic principles of molecular populaton genetics and evolution as applied to analysis of genome data. Some computer analysis of genome data will be performed.

Genome 562: Population Genetics
Instructors: Alison Feder, Kelley Harris

Genome 465 / 565: Advanced Human Genetics
Instructors: Mary-Claire King, Evan Eichler
TAs: Caroline Kikawa, Jenny Nathans

Course Description:
Explores genetic analysis of naturally occurring variation in humans; origins and consequences of mutation, as mediated by selection, migration, population structure and drift; approaches to finding human disease genes and characterizing them at the molecular level; relevance of to other species to analysis of human genes. Prerequisite: either Genome 361 or Genome 371.

 

Spring 2025

Genome 361: Fundamentals of Genetics and Genomics
Instructors:  Leo Pallanck, Jim Thomas, Hannah Jordt
TAs: Connor Finkbeiner, Sophia Gibson, Samantha Hardy, Alex Orellana, Philippa Steinberg, Bo Wen

Course Description:
Introduces fundamentals concepts in genetics and genomics including patterns of inheritance, genetic variation, and the relationship between genotype and phenotype. Prerequisite: Biol 200; may not be taken if Genome 371 has already been taken; may not be repeated. Offered: AWSpS

Genome 373: Genome Informatics
Instructors: Alison Feder, Doug Fowler
TA: Malvika Tejura

Course Description:
Focuses on methods for analyzing large genetic data sets and their application to biological problems, including sequence alignment and search methods, gene prediction, phylogenetic trees, and microarray analysis.

Genome 475: Debates in Genetics
Instructors: Devin Schweppe, Lea Starita
TA: Elliott Swanson

Course Description:
Utilizes the original scientific literature as the basis for discussion of a range of genetic issues that impact society Discussions are student-led; evaluations are based both on participation in class and on a research paper. Prerequisite: Prerequisite: BIOL 200; either BIOL 355, BIOL 401, BIOL 402, GENOME 361, or GENOME 371.

Genome 490: Undergraduate Seminar
Instructor: Jay Shendure
specific topic tba

Genome 541: Intro to Computational Molecular Biology II
Instructor: Bill Noble

Course Description:
Computational methods for studying molecular evolution. Students must be able to write computer programs for data analysis. Prior coursework in biology and probability highly desirable Prerequisite: GENOME 540 or permission of instructor.

Genome 553: Genetic Analysis
Instructor: Celeste Berg
10 week course, one session per week

Course Description:
Discusses methods for selectively removing, adding, or altering specific proteins, to identify and order genes in a pathway, define protein function, determine tissue and temporal requirements for gene function, and distinguish among competing hypotheses to explain biological phenomena. Formerly called GENET 551. Prerequisite: GENOME 371, GENOME 551 or equivalent.

Genome 560: Statistics for Genome Sciences
Instructors: Devin Schweppe, Maggie Russell
TA: Shruti Jain

Genome 569: Bioinformatics Workflows for High-Throughput Sequencing Experiments
Instructor: Cole Trapnell
5 week course - first half of the quarter

Course Description:
Programming skills and software tools for building automated bioinformatics pipelines and computational biology analyses. Emphasis on UNIX tools and R libraries for distilling raw sequencing data into interpretable results. For students familiar with UNIX and with some programming experience in Python, R, or C/C++.

Genome 575: Instrumentation
Instructors: Brian Beliveau, Mike MacCoss

Genome 580: Ethics in Biomedical Research
Instructor: Mike MacCoss
5 week course - exact schedule to be determined

Course Description:
Explores ethical issues in research and teaching and discusses avenues of responsible conduct. Intended for second year Genome Sciences grads (except for MSTP students, who take this in year 3) and others supported by departmental training grants.

 

Summer 2024

Genome 361 : Fundamentals of Genetics and Genomics
Instructor: Hannah Jordt
TA: Qi Yu

Course Description:
Introduces fundamentals concepts in genetics and genomics including patterns of inheritance, genetic variation, and the relationship between genotype and phenotype. Prerequisite: Biol 200; may not be taken if Genome 371 has already been taken; may not be repeated. Offered: AWSpS