Drugs | Y5D3 | Pf (D6) | Pf (Mik) | Human | BCp | HCp | Tg | Pc |
PT Series | DHFR | DHFR | DHFR | DHFR | DHFR-TS | DHFR-TS | DHFR | DHFR |
182 | - | 3.07 | 1.23 | 0.67 | 0.63 | - | - | - |
183 | - | 3.23 | 1.37 | 0.70 | 0.67 | 0.63 | 0.67 | - |
186 | - | 2.33 | 0.93 | - | - | - | - | - |
187 | - | 3.15 | 1.40 | 0.85 | 1.10 | 0.80 | - | - |
196 | - | 3.25 | 1.00 | - | - | - | - | - |
228 | - | 2.15 | 0.85 | - | - | - | - | - |
235 | - | 1.75 | - | - | - | - | - | - |
262 | - | 2.30 | 0.85 | - | 0.65 | 0.65 | 0.65 | - |
263 | - | 1.65 | - | - | 0.65 | 0.65 | - | - |
264 | - | 2.70 | 0.95 | 1.20 | 1.10 | 0.70 | - | 1.10 |
265 | - | 2.25 | - | - | - | - | - | - |
266 | - | 1.60 | - | - | 0.70 | - | - | - |
267 | - | 1.30 | - | - | - | - | - | - |
268 | - | 1.70 | - | - | - | - | - | - |
269 | - | 0.70 | - | - | - | - | - | - |
271 | - | 2.10 | - | - | - | - | - | - |
301 | - | 2.20 | - | - | 0.75 | 0.65 | - | - |
304 | - | 1.00 | - | - | - | - | - | - |
310 | - | 1.00 | - | - | - | - | - | - |
312 | - | 1.45 | - | - | - | - | - | - |
313 | - | 1.50 | - | - | - | - | - | - |
315 | - | 0.65 | - | - | - | - | - | - |
323 | - | 1.95 | 0.80 | - | - | - | 0.75 | - |
328 | - | 1.65 | - | 0.65 | 0.65 | - | - | - |
331 | - | 3.00 | - | - | - | - | - | - |
333 | - | 0.85 | - | - | - | - | - | - |
653 | - | 1.50 | - | - | - | - | - | - |
658 | - | 1.83 | - | - | - | - | - | - |
659 | - | 2.70 | 1.10 | - | 0.67 | 0.67 | - | 0.63 |
660 | - | 3.10 | 1.40 | 0.63 | 0.70 | 0.67 | - | - |
661 | - | 3.43 | 1.70 | - | 0.70 | 0.70 | 0.63 | 0.87 |
PY Series | ||||||||
838 | - | 3.27 | 1.90 | 1.97 | 1.90 | 1.87 | 2.03 | 0.67 |
839 | - | 3.10 | 1.93 | 1.70 | 0.90 | 1.17 | 2.03 | - |
840 | - | 2.43 | 0.63 | - | 0.63 | 0.63 | - | - |
846 | - | 2.93 | 2.67 | 0.70 | 0.77 | 0.63 | 1.50 | 0.77 |
847 | - | 2.53 | 0.70 | - | - | - | - | - |
848 | - | 2.13 | 0.63 | - | - | - | - | - |
850 | 0.63 | 2.77 | 2.47 | 2.10 | 1.90 | 1.73 | 2.40 | 1.37 |
851 | - | 2.90 | 2.57 | 2.40 | 1.90 | 1.73 | 2.47 | 1.37 |
855 | - | 2.30 | 0.70 | - | - | - | 0.73 | - |
856 | 0.87 | 3.27 | 3.10 | 2.50 | 2.73 | 2.87 | 2.70 | 2.13 |
857 | - | 2.07 | 0.83 | - | - | - | 0.70 | - |
858 | - | 3.23 | 1.87 | 1.27 | - | - | 0.70 | - |
859 | - | 3.37 | 2.90 | 2.40 | 2.53 | 2.43 | 2.63 | 1.50 |
861 | 0.63 | 2.07 | 1.00 | 0.70 | 0.80 | 0.83 | 0.87 | 0.67 |
862 | - | 2.87 | 1.30 | 1.23 | 0.80 | 0.80 | 1.03 | - |
865 | - | 1.43 | 0.70 | 0.63 | 0.67 | 0.63 | 0.67 | - |
866 | - | 2.00 | - | - | - | 0.63 | 0.63 | - |
867 | - | 1.77 | 0.67 | - | 0.63 | 0.63 | 0.67 | - |
868 | - | 3.20 | 2.60 | 1.63 | 0.73 | 0.73 | 1.40 | 0.73 |
869 | - | 0.80 | - | - | - | - | - | - |
870 | - | 1.50 | - | - | - | - | - | - |
871 | - | 3.17 | 2.33 | 1.10 | 0.97 | 0.93 | 1.10 | 0.67 |
873 | - | 3.47 | 2.00 | 1.30 | 1.13 | 0.90 | 1.23 | - |
874 | - | 3.43 | 2.90 | 2.53 | 2.10 | 2.10 | 2.13 | 1.20 |
876 | 1.33 | 3.83 | 3.50 | 2.93 | 2.33 | 2.10 | 2.33 | 1.87 |
877 | 1.60 | 3.73 | 3.47 | 2.67 | 2.73 | 2.53 | 2.53 | 2.00 |
878 | 1.27 | 3.53 | 2.93 | 2.40 | 2.30 | 2.07 | 2.00 | 1.67 |
879 | - | 2.40 | 0.83 | - | 0.67 | 0.70 | 0.77 | - |
880 | - | 2.53 | 1.13 | - | 1.03 | 0.80 | 1.07 | 0.63 |
883 | 0.63 | 2.13 | 0.63 | - | 0.63 | 0.63 | 0.63 | - |
884 | - | 3.20 | 2.23 | 0.90 | 0.73 | 0.70 | 0.93 | 0.70 |
887 | - | 1.97 | - | - | - | - | - | - |
889 | - | 2.47 | 0.63 | - | 0.63 | - | - | - |
895 | - | 2.57 | 0.63 | - | 0.63 | 0.63 | - | - |
897 | 1.00 | 3.77 | 3.37 | 2.47 | 2.50 | 2.17 | 2.37 | 1.60 |
900 | 1.63 | 3.83 | 3.77 | 3.13 | 3.20 | 2.80 | 3.27 | 2.63 |
901 | 0.93 | 3.47 | 3.30 | 2.30 | 2.23 | 1.97 | 2.53 | 1.67 |
902 | - | 2.50 | - | - | - | - | - | - |
903 | - | 3.60 | 3.43 | 2.27 | 0.93 | 0.73 | 1.80 | 1.30 |
905 | 1.43 | 3.90 | 3.80 | 3.57 | 3.43 | 3.37 | 3.37 | 2.87 |
907 | - | 3.37 | 2.90 | 2.10 | 2.27 | 2.30 | 2.33 | 1.33 |
908 | 1.30 | 3.80 | 3.87 | 3.23 | 3.07 | 2.73 | 3.13 | 2.27 |
909 | 1.10 | 3.70 | 3.73 | 2.87 | 2.90 | 2.57 | 2.97 | 1.93 |
910 | 0.93 | 3.80 | 3.77 | 3.07 | 3.10 | 2.87 | 3.03 | 1.80 |
911 | 1.07 | 3.37 | 2.73 | 1.97 | 2.17 | 2.10 | 2.17 | 1.47 |
912 | - | 2.77 | 1.17 | - | 0.67 | 0.63 | 0.67 | - |
913 | - | 3.13 | 0.77 | - | - | - | 0.63 | - |
915 | 1.27 | 3.73 | 3.57 | 3.10 | 2.70 | 2.53 | 3.13 | 2.50 |
916 | 0.80 | 3.87 | 3.53 | 2.47 | 2.20 | 2.03 | 2.47 | 1.53 |
917 | 0.97 | 3.73 | 3.57 | 2.77 | 2.57 | 2.47 | 2.97 | 2.27 |
918 | - | 3.37 | 2.83 | 1.07 | 1.03 | 0.73 | 1.93 | - |
919 | 1.37 | 3.40 | 3.07 | 2.03 | 2.00 | 1.83 | 2.30 | 1.83 |
920 | 1.07 | 3.73 | 3.63 | 2.77 | 2.77 | 2.60 | 2.80 | 2.20 |
922 | - | 2.40 | 1.47 | 0.63 | - | - | 0.73 | 0.80 |
This chart displays the inhibition values for each test compound against the various yeast strains.
All values were obtained by measuring from the center of each plate to the point of yeast growth.
Measurements were done in centimeters and a "-" represents a failure by that compound to inhibit the yeast (<.6cm)
Last Updated on 9/19/2000
By Genetics Office