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PAML is a program package for phylogenetic analyses of DNA or protein sequences using maximum likelihood:
http://abacus.gene.ucl.ac.uk/software/paml.html

Phred/Phrap/Consed is used to make base calls and assemble Chromatograms into reads. Assemblies are visualized using Consed:
http://www.phrap.org/

PolyPhred is a program that identifies heterozygous sites for single nucleotide substitutions:
http://droog.gs.washington.edu/PolyPhred.html

MEGA is an integrated tool for automatic and manual sequence alignment, inferring phylogenetic trees, mining web-based databases, estimating rates of molecular evolution, and testing evolutionary hypotheses:
http://www.megasoftware.net/mega3/

Single Likelihood Ancestor Counting (SLAC) analysis , a heavily modified and efficiently implemented version of the Suzuki-Gojobori method (*), to identify positively and negatively selected sites in codon alignments of up to 150 sequences and up to 10000 codons:
http://www.datamonkey.org/

HYPHY is a software package intended to perform maximum likelihood analyses of genetic sequence data and equipped with tools to test various statistical hypotheses:
http://www.hyphy.org/

SMART, Simple Modular Architecture Research Tool for visualizing protein structure:
http://smart.embl-heidelberg.de/

Arlequin is a population genetics software able to handle large samples of molecular data (RFLPs, DNA sequences, microsatellites), while retaining the capacity of analyzing allele frequency data:
http://lgb.unige.ch/arlequin/

Se-Al, manual sequence alignment editor for the Macintosh:
http://evolve.zoo.ox.ac.uk/software/seal/

Other useful sites:

http://genome.ucsc.edu/

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