John Storey

Associate Professor of Genome Sciences and of Biostatistics

Office Phone: (206) 616-8078
Fax: (206) 543-3286
Office Location: Foege S103B, Box 355065
Email: jstorey (at) u.washington.edu
Website

Research:

The goal of our research is to develop statistical methods useful in understanding genome-wide data, such as that resulting from DNA microarrays, large scale genotyping, or genome sequencing. This involves developing techniques for making inferences and/or predictions on large data sets, while taking biological knowledge into account whenever possible. A significant component of our research is to also collaborate with biologists on laboratory experiments. The overall goal is to contribute to a quantitative understanding of the molecular biology of cells and the genetic basis of human disease.

Selected Publications:

Storey JD, Xiao W, Leek JT, Tompkins RG, and Davis RW. (2005) Significance analysis of time course microarray experiments. Proceedings of the National Academy of Sciences, 102: 12837-12842.

Brem RB*, Storey JD*, Whittle J, and Kruglyak L. (2005) Genetic interactions between polymorphisms that affect gene expression in yeast. Nature, 436: 701-703. *Equal contributors.

Storey JD, Akey JM, and Kruglyak L. (2005) Multiple locus linkage analysis of genomewide expression in yeast. PLoS Biology, 3(8): 1380-1390.

Storey JD and Tibshirani R. (2003) Statistical significance for genome-wide studies. Proceedings of the National Academy of Sciences, 100: 9440-9445.

Wang Y, Liu CL, Storey JD, Tibshirani RJ, Herschlag D, and Brown PO. (2002) Precision and functional specificity in mRNA decay. Proceedings of the National Academy of Sciences, 99: 5860-5865.

Storey JD and Siegmund D. (2001) Approximate p-values for local sequence alignments: numerical studies. Journal of Computational Biology, 8: 549-556.

additional publication listings available via PubMed