John Stamatoyannopoulos

Associate Professor of Genome Sciences and Medicine

phone (Foege office): (206) 685-2672 | fax: (206) 267-1094
phone (Elliott lab office): (206) 267-1098
Foege S-310A, Box 355065
jstam [ a t ]

Dr. Stamatoyanopoulos graduated from Stanford University in 1990 with degrees in Biology, Symbolic Systems, and Classics, and received an M.D. in 1995 from the University of Washington. He completed residency in Internal Medicine at Brigham and Women's Hospital, Harvard Medical School, and was a fellow in Oncology and Hematology at Dana Farber Cancer Institute and the Massachusetts General Hospital. Dr. Stamatoyannopoulos joined the Departments of Genome Sciences and Medicine (Oncology) at the University of Washington in 2005.

Dr. Stamatoyannopoulos' laboratory focuses on elucidating eukaryotic regulatory programs through the application of genome-scale molecular and computational technologies.  Major ongoing efforts are (i) to delineate the cis-regulatory architecture of the human and mouse genomes; (ii) to map and analyze transcription factor regulatory networks; and (iii) to determine the functional consequences of disease-associated non-coding variation in regulatory DNA.  He directs the UW ENCODE Project, a component of the NHGRI program to map all of the functional elements in the human genome.  He also directs the Northwest Reference Epigenome Mapping Center funded by the NIH Roadmap Epigenomics program, and oversee the High-Throughput Genomics Center at UW, which provides large-scale sequencing and epigenetic analysis capabilities to diverse investigators. 

Research areas:
·         Regulatory DNA
·         Gene Regulation and Common Disease
·         Development and Differentiation
·         Regulatory Networks
·         Technology Development
·         DNA Replication

Selected Publications:

please see the Stamatoyannopoulos Lab website